The CANTO Study is evaluating an investigational study drug to see if it is effective, safe, and tolerated for people with depression associated with Bipolar I or Bipolar II Disorder.

This study is open to persons aged 18 to 65. To participate, you must have a diagnosis of Bipolar I or II Disorder and be experiencing depression for at least 1 month but not longer than 12 months.

Get started – see if you are eligible brush

You may qualify for the CANTO Study if you:

  • Are between the ages of 18-65 years old
  • Have a diagnosis of Bipolar I or Bipolar II Disorder
  • Are experiencing depression for at least 1 month, but not longer than 12 months
Participate

Your participation in this study is voluntary. You may decide not to participate or stop participation in this study at any time. Qualified participants may be eligible to receive compensation.

Sign Up

What happens if I sign up? We will match you to a study location in your area or notify you when one becomes available. The study team will then contact you and you may have the opportunity to participate if qualified.

If you think you might like to participate in the CANTO Study or would like more information, please enter your information below so we can see if you may qualify and can contact you about the study. Keep in mind that participation is entirely voluntary. If you do decide to take part in a study, you may change your mind about participating at any time.

Frequently Asked Questions

What is a study?

A study (also called a clinical trial) is medical research that helps to answer important questions about an investigational drug – these may include how well an investigational study drug works for a certain condition. All medications must be tested in clinical research studies before they can be approved and prescribed to patients.

A study is the process by which new and innovative medications and treatments are approved, to treat illnesses. All medications, whether a prescription written by a doctor or purchased at a store, such as , headache or allergy medicines, have gone through the clinical research study process before it was available at your local pharmacy.

Your participation in this study is voluntary. You may decide not to participate or stop participation in this study at any time. Qualified participants may be eligible to receive compensation.

The research team will be able to explain more about what the CANTO Study will involve, and it is up to you to decide if you want to take part. Participation in this study is voluntary. If you decide to participate, you are free to withdraw at any time without affecting those relationships.

We match you to a study site within a close travel distance from your home. If we are not running the study in your area currently, with your permission, we will keep you in our database and reach out once a study in your area becomes available. If, at any time, you decided you no longer want your information stored, you can opt out and we will delete your details.

About the CANTO Study

The CANTO Study is open to persons aged 18 to 65. To participate, you must have a diagnosis of Bipolar I or II disorder and be experiencing depression for at least 1 month but not longer than 12 months.

This study will enroll 160 participants across 40 study sites. The study lasts approximately 13 weeks. Six visits will take place at the study site. Three visits will occur via phone. While you are participating, all study-related care will be provided at no cost to you. You do not need health insurance to participate.

Screening assessments will be done to determine if you are eligible for this study. If you qualify and decide to take part in this study, you will be randomly assigned to receive either the investigational study drug or placebo. The placebo looks the same as the investigational study drug but is not expected to have any effects on the body. Neither you nor the study doctor and staff will know what treatment you are assigned to receive.

Participate

Who can take part in the CANTO Study?

You may qualify for the CANTO Study if you:

  • Are between the ages of 18-65 years old
  • Have a diagnosis of Bipolar I or Bipolar II Disorder
  • Are experiencing depression for at least 1 month, but not longer than 12 months